Index/Topics/FDA-approved weight-loss medications

FDA-approved weight-loss medications

The FDA has approved several weight-loss medications, including GLP-1s and related multimodal peptides, which have shown significant weight loss in clinical trials.

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5 results
Jan 12, 2026

What are the clinically proven differences between GLP‑1 prescription drugs and over‑the‑counter weight‑loss supplements?

Prescription GLP‑1 receptor agonists are clinically tested, regulated drugs that mimic the GLP‑1 hormone to slow gastric emptying, reduce appetite and produce substantial, trial-proven weight loss, wh...

Jan 11, 2026

Are GLP-1 medications safe?

GLP-1 receptor agonists are effective medicines that have transformed diabetes and obesity treatment, delivering substantial weight loss and cardiovascular and metabolic benefits in trials and real-wo...

Jan 9, 2026

What clinical trials support GLP‑1 drugs for weight loss compared to lifestyle interventions?

Randomized clinical trials have shown GLP‑1 receptor agonists produce substantially greater average weight loss than lifestyle interventions alone in protocolized studies—examples include semaglutide ...

Jan 7, 2026

What peer‑reviewed evidence exists for common ingredients claimed to boost metabolism in over‑the‑counter weight loss supplements?

Peer‑reviewed clinical reviews and meta‑analyses show a mixed, mostly modest body of evidence that a handful of common over‑the‑counter ingredients—caffeine and green tea catechins (often together), s...

Jan 7, 2026

What are the FDA‑approved prescription weight‑loss medications and how do their typical effects compare to GLP‑1 drugs?

A raft of FDA‑approved prescription weight‑loss medications exists beyond the spotlighted GLP‑1 class — older drugs like phentermine and orlistat remain approved even as GLP‑1s and related multimodal ...