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Fentanyl synthesis routes

Methods used for illicit fentanyl synthesis, including the Siegfried/Janssen methods

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Jan 13, 2026
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What alternative chemical precursors for fentanyl synthesis have emerged since 2017 and how are they regulated internationally?

The international response to fentanyl precursors has evolved from scheduling two core chemicals in 2017 to a rolling effort through 2024 to add multiple alternative precursors as traffickers shifted ...

Jan 17, 2026

How do forensic toxicologists interpret fentanyl and methamphetamine blood levels in post-mortem testing?

Forensic toxicologists treat post-mortem fentanyl and methamphetamine blood numbers as one piece of evidence, not a standalone “smoking gun,” because postmortem redistribution (PMR), sampling site, ti...