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Index/Topics/Genetic Defects

Genetic Defects

Genetic defects, such as ABCB1 nonsense mutations, and their impact on ivermectin safety.

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3 results
Feb 1, 2026
Most Viewed

What are the clinical signs and timeline of ivermectin overdose in adults and children?

in humans most commonly produces gastrointestinal upset, circulatory instability and a range of neurological symptoms that can progress from lethargy and confusion to seizures, coma and rarely death; ...

Jan 27, 2026

What are documented outcomes and follow‑up durations in human case series of severe ivermectin overdose?

Human case series and reports of severe document a spectrum of outcomes ranging from full recovery after supportive care to prolonged neurologic injury and death; reported follow‑up intervals are hete...

Jan 16, 2026

What is the dose‑response relationship for ivermectin adverse events across controlled human trials?

Controlled human trials and systematic reviews conducted to date do not demonstrate a clear, consistent dose–response increase in adverse events for ivermectin across the common therapeutic range and ...

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