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Gleason Grade Group is used to counsel about progression risk and to inform recommendations for early sRT.
Gleason score and PSA doubling time (PSADT) are strong, largely independent predictors of metastatic progression after radical prostatectomy, with higher Gleason grades and shorter PSADTs both linked ...
Salvage radiotherapy (sRT) planning should synthesize PSA kinetics (especially PSA doubling time), PSMA-PET findings, pathologic Gleason Grade Group, and margin status to stratify risk, decide on targ...
Modern "ultrasensitive" PSA assays push analytic detection down into the picogram-per-milliliter range—commonly reported as limits between roughly 0.001 and 0.003 ng/mL (1–3 pg/µL) and historically as...
Androgen‑deprivation therapy (ADT) should be added to salvage radiotherapy (SRT) after radical prostatectomy when biochemical recurrence (BCR) is accompanied by high‑risk features—most guidelines and ...
usually indicates low short-term risk of aggressive, screen-detectable prostate cancer, with very low event rates for aggressive disease over 5–15 years in population cohorts . However, a distinct, cl...