Index/Topics/GLP-1 Receptor Agonists Weight Regain

GLP-1 Receptor Agonists Weight Regain

The topic is about the weight regain after stopping GLP-1 receptor agonists, including the effects of the drug on appetite signaling and the physiological defenses triggered by weight loss.

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Jan 13, 2026
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What are the long‑term weight maintenance outcomes after stopping GLP‑1 therapy like semaglutide?

Clinical trials and systematic reviews consistently show that stopping GLP‑1 receptor agonists such as semaglutide is commonly followed by clinically meaningful weight regain — often returning a large...

Jan 21, 2026

How quickly does weight typically return after stopping GLP‑1 therapy and what strategies exist to maintain weight loss?

commonly leads to clinically meaningful weight regain within months to a year, though individual trajectories vary; randomized trials show much of the lost weight returns within 6–12 months and meta-a...

Jan 21, 2026

What are the average weight loss results for patients taking semaglutide with cyanocobalamin?

A small real‑world retrospective study of compounded once‑weekly combined with cyanocobalamin found an average weight loss of 4.11 kg (4.57% of starting weight) after three months, with most of the lo...

Jan 18, 2026

What protocols have been tested to prevent metabolic rebound after stopping GLP‑1 receptor agonists?

Clinical trials and systematic reviews consistently document clinically meaningful metabolic and weight rebound after stopping GLP‑1 receptor agonists, and while commentators and reviews urge “structu...

Jan 16, 2026

What clinical trial evidence exists for Gelatide (or similar weight‑loss supplements) in humans and what adverse events have been reported?

There are no clinical-trial documents in the supplied reporting that evaluate a product named “Gelatide,” so claims about its safety or efficacy cannot be corroborated from these sources; instead, the...