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GLP-1/GIP drugs weight loss

GLP-1/GIP drugs produce substantial weight loss and short-term improvements in cardiometabolic markers while on treatment, but those gains largely reverse after stopping therapy

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Jan 12, 2026

How does remission achieved with GLP‑1/GIP drugs compare to remission after stopping the drugs in randomized trials?

Randomized trials show GLP‑1 and GLP‑1/GIP drugs (like semaglutide and tirzepatide) produce substantial weight loss and short‑term improvements in cardiometabolic markers while on treatment, but those...