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Index/Topics/Grapefruit-Drug Interactions

Grapefruit-Drug Interactions

Interactions between grapefruit and drugs metabolized by CYP3A4, resulting in increased systemic exposure to these drugs.

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3 results
Jan 29, 2026
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What are the documented side effects of hawthorn, gotu kola, grape seed extract and ginseng in controlled studies?

and safety reviews report few acute harms from and when used short-term, but signal important drug interactions and cardiovascular effects for hawthorn and , and rare but serious liver injury and seda...

Jan 22, 2026
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is it possible to do drugs while drinking lemonade

Yes — people can and do consume recreational drugs while drinking , and in some cases lemonade (or lemonade powder/juice) is intentionally used to prepare or mask drugs; however, the safety and pharma...

Jan 16, 2026
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Which prescription drugs metabolized by CYP3A4 have documented interactions with herbal supplements?

St. John’s wort, grapefruit (juice), and a range of polyphenol-rich herbal supplements have documented, clinically significant interactions with prescription drugs that are substrates of CYP3A4, alter...

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