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Hedgehog Pathway Inhibition

The process of inhibiting the Hedgehog signaling pathway, which is implicated in the development of basal cell carcinoma.

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Jan 27, 2026
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What clinical trials have tested repurposed drugs (like itraconazole or remetinostat) for basal cell carcinoma and what were their outcomes?

Two repurposed drugs have reached human trials for (BCC): the oral antifungal itraconazole, tested in a small phase II open‑label study that showed suppression and modest tumor shrinkage (supporting t...