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Heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is an autoimmune syndrome that resembles VITT/TTS mechanistically.

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Jan 12, 2026
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What genetic or immune risk factors have been identified that predispose people to VITT after adenovirus‑vector COVID‑19 vaccines?

Vaccine‑induced immune thrombotic thrombocytopenia (VITT) is driven by platelet‑activating antibodies against platelet factor 4 (PF4), and those antibodies are the central immune correlate that distin...