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High-dose N-acetylcysteine

The use of high-dose N-acetylcysteine to increase intracellular glutathione levels in humans.

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Jan 23, 2026
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What are the safety, dosing, and pharmacokinetic limitations of high‑dose NAC for targeting intracellular glutathione in humans?

() can increase systemic cysteine availability and has a generally favorable safety profile in many clinical trials, but pharmacokinetic limits, route‑dependent adverse events, and uncertain translati...

Feb 3, 2026

How effective is N-acetylcysteine or glutathione in treating cadmium toxicity?

show consistent protective effects against cadmium (Cd) in cell and animal studies—reducing reactive oxygen species, restoring glutathione-dependent enzyme activity, and preventing apoptosis and organ...