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Index/Topics/Hormone Replacement Therapy

Hormone Replacement Therapy

The use of hormone replacement therapy, particularly in transmasculine individuals

Fact-Checks

3 results
Jan 22, 2026

How do vocal outcomes differ between transmasculine gender-affirming regimens and low-dose therapeutic testosterone in cisgender women?

regimens typically produce larger, faster, and more reliably masculinizing shifts in fundamental frequency (pitch) and perceived vocal masculinity than low-dose therapeutic testosterone given to cisge...

Jan 11, 2026

What evidence exists on the impact of menopause treatments on vaginal anatomy and sexual comfort?

Menopause-related hypoestrogenism causes thinning, dryness and changes in vaginal anatomy (GSM) that commonly reduce sexual comfort, and a body of clinical evidence shows that local vaginal estrogens,...

Jan 11, 2026

What treatments reduce vaginal atrophy and lower risk of tearing after menopause?

Vaginal atrophy (genitourinary syndrome of menopause) is driven by estrogen loss and is commonly treated effectively with local low‑dose vaginal estrogen, which restores tissue thickness, elasticity a...

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