Index/Topics/Hormone therapy

Hormone therapy

The use of hormones as part of gender transition, and the potential for regret among those who undergo hormone therapy.

Fact-Checks

5 results
Jan 27, 2026
Most Viewed

What treatment options (hormone therapy, surgery, counseling) are available and what are their risks and outcomes?

Three broad treatment pathways are used for —psychosocial support, , and surgery—and each carries potential benefits (reduced distress, improved self-reported mental health) and measurable risks (medi...

Jan 22, 2026
Most Viewed

Are there contraindications for prostate play with prostate cancer or after prostate surgery?

Prostate play after a diagnosis of or following prostate surgery carries specific risks tied to common treatment side effects—most importantly , , urethral strictures or anastomotic leaks, and changes...

Jan 13, 2026
Most Viewed

How do hormonal treatments compare to psychotherapy or relationship counseling for treating low sexual desire?

Hormonal treatments (estrogens, tibolone, androgens) produce small but measurable improvements in sexual function and desire—most consistently in peri- and postmenopausal women—whereas psychotherapy a...

Feb 4, 2026

What is the actual rate of people who regret transitioning

Medical and surgical studies consistently find that explicit, sustained is uncommon—typically reported at well under 1% in recent systematic reviews of surgical cohorts —but the true rate of regret ac...

Jan 11, 2026

What evidence exists on the impact of menopause treatments on vaginal anatomy and sexual comfort?

Menopause-related hypoestrogenism causes thinning, dryness and changes in vaginal anatomy (GSM) that commonly reduce sexual comfort, and a body of clinical evidence shows that local vaginal estrogens,...