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The formulation and use of ivermectin in human medicine
Human-prescription ivermectin is dosed in micrograms per kilogram (commonly 150–200 mcg/kg as a single dose for approved indications), formulated and labeled for oral tablets or topical creams with co...
No published study has directly measured ivermectin concentrations in human lung tissue after repeated oral dosing; investigators therefore rely on animal lung concentrations, human plasma PK, and phy...
Veterinary ivermectin formulations differ from human prescriptions primarily in concentration, formulation type, and inactive ingredients: animal products are made as high‑strength injectables, pour‑o...
Veterinary (horse) ivermectin pastes and human ivermectin tablets contain the same active molecule (ivermectin) but differ in formulation: veterinary pastes include excipients and additives tailored t...
Modern laboratories detect ivermectin in blood, plasma, tissue and environmental matrices using a suite of chromatographic and immunoassay techniques; tandem mass spectrometry methods (LC–MS/MS or UHP...
Ivermectin–used widely as an antiparasitic and explored as a repurposed drug–is associated with renal findings only rarely and usually mildly (transient proteinuria or minor tubular markers), and larg...
Human prescription ivermectin is supplied as regulated, weight‑based oral tablets or topical formulations at low, controlled strengths for single‑dose or short‑course use (typically ~0.15–0.20 mg/kg f...
Veterinary ivermectin products for horses are manufactured in far higher-strength, differently formulated forms—such as concentrated oral pastes, large-dose injectables, and pour-on liquids—than human...