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Index/Topics/Hypothalamic-Pituitary-Gonadal Axis

Hypothalamic-Pituitary-Gonadal Axis

The role of the HPG axis in regulating puberty, including the influence of leptin and other signals.

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2 results
Jan 11, 2026

how does body fat affect puberty?

Higher body fat is consistently associated with earlier pubertal timing in girls and more complex, inconsistent effects in boys; adipose-derived signals—especially leptin—appear to be permissive for p...

Jan 5, 2026

How do hormones affect yearly penile growth during adolescence?

Hormones—chiefly luteinizing hormone (LH) from the pituitary and its downstream effector testosterone—are the proximate drivers of penile growth from infancy through adolescence, with androgen exposur...

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