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Index/Topics/Immunogenicity

Immunogenicity

The ability of a vaccine to induce an immune response

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2 results
Feb 1, 2026

Could Toxoplasma gondii–derived antigens be developed as immunotherapy adjuncts for human pancreatic cancer and what clinical trials exist?

Preclinical literature shows consistent, reproducible evidence that attenuated Toxoplasma gondii strains and –derived antigens (for example, soluble Toxoplasma antigen [STAg] and profilin) can reprogr...

Jan 22, 2026

How do SARS-CoV-2 variants like Omicron specifically reduce vaccine effectiveness and what lab and epidemiologic evidence supports immune escape?

Variants such as reduce vaccine effectiveness primarily by accumulating mutations in the Spike protein that change antibody binding sites, producing antigenic mismatch to vaccine-elicited antibodies a...