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Index/Topics/Immunosuppressive tumor microenvironment

Immunosuppressive tumor microenvironment

The environment surrounding a tumor that suppresses the immune system

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Feb 1, 2026

Could Toxoplasma gondii–derived antigens be developed as immunotherapy adjuncts for human pancreatic cancer and what clinical trials exist?

Preclinical literature shows consistent, reproducible evidence that attenuated Toxoplasma gondii strains and –derived antigens (for example, soluble Toxoplasma antigen [STAg] and profilin) can reprogr...

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