Index/Topics/Intracavernosal Stem Cell Therapy and PRP for ED

Intracavernosal Stem Cell Therapy and PRP for ED

The use of intracavernosal stem cell therapy and platelet-rich plasma (PRP) for erectile dysfunction (ED) is not endorsed by major urology guideline bodies due to limited clinical evidence and safety concerns.

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Jan 12, 2026
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How does timing (early vs delayed) of VED or PDE‑5 inhibitor initiation affect penile length preservation and long‑term erectile outcomes?

Early initiation of penile rehabilitation—either with vacuum erectile devices (VEDs) or chronic/regular phosphodiesterase‑5 inhibitors (PDE5‑Is)—is plausibly associated with better preservation of str...

Jan 16, 2026
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What are evidence‑based first‑line treatments for erectile dysfunction and when should a specialist be consulted?

Phosphodiesterase type 5 inhibitors (PDE5i) — oral drugs such as sildenafil — are the evidence‑based, guideline‑recommended first‑line pharmacologic treatment for most men with erectile dysfunction (E...

Jan 20, 2026

What are the differences between premature ejaculation and delayed ejaculation in young versus older adults?

Premature ejaculation (PE) and delayed ejaculation (DE) sit at opposite ends of the ejaculatory spectrum, and age reshapes how often they appear, why they appear, and how clinicians classify them: PE ...

Jan 19, 2026

erectile dysfunction

Erectile dysfunction (ED) is a common, often treatable medical condition defined by the recurrent inability to achieve or maintain an erection sufficient for satisfactory sexual activity, and it frequ...

Jan 15, 2026

Which heart conditions make vacuum erection devices dangerous?

Vacuum erection devices (VEDs) are widely described as a generally safe, mechanical option for erectile dysfunction and are explicitly recommended for many men with vascular causes of ED, including he...

Jan 11, 2026

What do urology societies recommend about frequency and duration of vacuum therapy?

Major urology societies uniformly endorse vacuum erection devices (VEDs) as a legitimate, non‑invasive option in the management of erectile dysfunction and as part of penile rehabilitation after radic...

Jan 9, 2026

Which lifestyle, medical, and pharmacologic treatments are recommended first-line for erectile dysfunction in current guidelines?

Current guideline-based care treats erectile dysfunction (ED) as a condition requiring both risk‑factor modification and shared decision‑making: lifestyle changes and management of comorbid disease ar...

Jan 9, 2026

How do urology professional societies (AUA, EAU) currently position vacuum erection devices in ED treatment algorithms?

American and European urology authorities position vacuum erection devices (VEDs) as established, non‑pharmacologic options that must be discussed with men who have erectile dysfunction, but neither s...

Jan 8, 2026

How do common L‑arginine dosages in commercial supplements compare to doses used in clinical trials for ED?

Commercial L‑arginine supplements and clinical research overlap but are not identical: randomized trials for vasculogenic erectile dysfunction most commonly test moderate-to-high doses around 1.5–6 g/...

Jan 8, 2026

Are stem cell or platelet-rich plasma therapies for erectile dysfunction supported by urology guidelines?

Major urology guideline bodies do not endorse routine clinical use of intracavernosal stem cell therapy or platelet‑rich plasma (PRP) for erectile dysfunction (ED): the American Urological Association...