Ivermectin as a cancer therapy

How do preclinical ivermectin dosing levels in mice compare with human pharmacokinetic tolerability in oncology studies?

Preclinical mouse studies of ivermectin report effective antitumor activity across a wide dose range—commonly 0.5–10 mg/kg and in some reviews up to 40 mg/kg—with many experiments using ~3–10 mg/kg to...