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Ivermectin Interaction with CNS Depressants

Ivermectin's potential to increase the risk of respiratory depression when combined with central nervous system depressants like benzodiazepines and opioids.

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Jan 10, 2026
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Does ivermectin interact pharmacologically with opioids or benzodiazepines to increase respiratory depression?

Ivermectin has biologic actions on GABAergic and benzodiazepine receptor systems in experimental models and public health agencies warn it can potentiate other central nervous system (CNS) depressants...