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Ivermectin has a wide range of documented and potential drug interactions
Ivermectin adverse effects follow multiple timelines: toxic neurologic or gastrointestinal effects from large or inappropriate doses can appear within hours, while parasite-related reactions and many ...
Ivermectin has documented interactions with a broad range of prescription drugs, including blood‑thinners (notably warfarin), drugs that depress the central nervous system (such as benzodiazepines and...
is mainly metabolized by the liver and excreted in feces, with less than 1% of unchanged drug found in urine, so routine dose adjustment for mild-to-moderate is generally not required . However, clini...
High‑dose ivermectin studies in humans and pharmacovigilance analyses document a spectrum of neurologic events—from common, mild symptoms such as dizziness and somnolence observed in trials to rare bu...
The literature documents a small but consistent signal that ivermectin can interact with hepatically metabolized drugs—most notably case reports and drug-interaction databases that link ivermectin wit...
Ivermectin has a wide range of documented and potential drug interactions; clinical resources list over 100 drugs that can interact with oral ivermectin, and the most commonly flagged ones fall into a...
’s interactions are driven mainly by effects on drug metabolism, transport proteins, and additive side-effect profiles, meaning it can both raise or lower levels of co‑administered drugs and magnify s...
High-dose and veterinary-use ivermectin have been linked repeatedly to neurological toxicity, gastrointestinal upset, and rising poison‑control calls during the era, while pharmacovigilance databases ...
There are no specific, documented drug–drug interactions between ivermectin and tamsulosin reported in the sources provided; major ivermectin interaction databases list many potential interacting drug...
High‑dose or prolonged ivermectin use has most often produced mild, transient symptoms—headache, dizziness, nausea, rash and gastrointestinal upset—across clinical studies, but rare serious events inc...
Ivermectin is primarily metabolized by hepatic CYP3A4 and is eliminated mostly in feces, so coadministration with other liver‑metabolized drugs or hepatic impairment can alter exposure and risk of tox...