Index/Topics/Ivermectin Overdose

Ivermectin Overdose

The risks of overdose and toxicity associated with using veterinary ivermectin in humans, including the differences in formulation and dosing.

Fact-Checks

10 results
Jan 16, 2026
Most Viewed

How often have ERs treated patients for horse ivermectin exposure in the last decade?

Emergency departments treated multiple documented cases of human ivermectin exposure tied to veterinary ("horse") formulations during the COVID-19 era, with poison centers and hospitals reporting an u...

Jan 30, 2026
Most Viewed

What have poison control centers and hospitals reported about ivermectin-related adverse events since OTC laws took effect?

Poison control centers and hospitals documented a clear surge in -related exposures and toxicity reports during the era, with public health agencies and academic centers citing increases in calls, eme...

Jan 27, 2026
Most Viewed

What are the recognized toxic effects and clinical management steps for ivermectin overdose?

most commonly produces gastrointestinal upset and a spectrum of neurologic effects ranging from dizziness and somnolence to confusion, ataxia, seizures, coma and, rarely, death; serious encephalopathy...

Jan 18, 2026

How have poison control call volumes and hospitalization rates changed during periods of ivermectin misuse?

Poison control centers and emergency departments reported marked increases in ivermectin exposure calls and associated emergency visits during waves of misuse in 2021, with multiple public-health advi...

Jan 16, 2026

What are the documented cases of ivermectin‑related neurotoxicity in humans and what were the contributing factors?

Documented human cases of ivermectin‑related neurotoxicity are rare but well described in the literature and fall into three broad patterns: mass‑treatment encephalopathies linked to parasitic coinfec...

Feb 4, 2026

Are dosages and concentrations different between horse paste ivermectin and human ivermectin formulations?

Horse (veterinary) and contain the same active molecule—ivermectin—but they differ markedly in concentration, labeled strength, delivery form, and recommended dosing, meaning horse paste is far more c...

Jan 13, 2026

Can ingestion of veterinary ivermectin cause toxic effects in humans beyond ivermectin itself?

Ingesting veterinary ivermectin can cause toxic effects in humans primarily because people take much larger doses than are safe for humans and because animal formulations contain inactive ingredients ...

Jan 10, 2026

What clinical case reports document co‑administration of ivermectin with benzodiazepines or opioids and respiratory depression?

A review of the available clinical case literature shows reports of neurological and respiratory depression after ivermectin overdose or toxicity, with several case series noting concomitant benzodiaz...

Jan 5, 2026

How common are renal adverse events with ivermectin compared with other antiparasitic or repurposed drugs?

Ivermectin–used widely as an antiparasitic and explored as a repurposed drug–is associated with renal findings only rarely and usually mildly (transient proteinuria or minor tubular markers), and larg...

Jan 5, 2026

How do concentrations of veterinary ivermectin products for horses differ from human formulations?

Veterinary ivermectin products for horses are manufactured in far higher-strength, differently formulated forms—such as concentrated oral pastes, large-dose injectables, and pour-on liquids—than human...