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The potential risks and side effects associated with ivermectin use
A body of pharmacokinetic studies finds that taking oral ivermectin with food — especially a high‑fat meal — tends to increase systemic exposure (AUC and sometimes Cmax) compared with fasting, but the...
Ivermectin is extensively metabolized by the liver and is eliminated mainly via feces rather than the kidneys, which helps explain why clinically significant renal clearance is minimal . Human pharmac...
Topical ivermectin has robust, phase‑level clinical trial evidence for two dermatologic uses beyond rosacea: as a 0.5% lotion for head lice (pediatrics and adults) and as a 1% cream primarily studied ...
Modern laboratories detect ivermectin in blood, plasma, tissue and environmental matrices using a suite of chromatographic and immunoassay techniques; tandem mass spectrometry methods (LC–MS/MS or UHP...
Veterinary ivermectin products for horses are manufactured in far higher-strength, differently formulated forms—such as concentrated oral pastes, large-dose injectables, and pour-on liquids—than human...
Formulating ivermectin with solubility enhancers such as polyvinylpyrrolidone (PVP) or arabinogalactan (AG) reliably increases apparent solubility and bioavailability and can permit lower effective do...