Index/Topics/Ivermectin Toxicity

Ivermectin Toxicity

Neurologic symptoms as the primary toxicity, and at least one death reported in the cohort—indicating that exposures have produced serious, sometimes life-threatening illness.

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24 results
Jan 26, 2026
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What are the overdose side effects of Ivermectin

can produce a spectrum of symptoms spanning gastrointestinal distress, cardiovascular instability, respiratory problems, and central nervous system toxicity, including altered mental status, seizures ...

Jan 12, 2026
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What are the documented adverse effects in humans at ivermectin doses ≥1 mg/kg or with parenteral administration?

Published human data document a consistent pattern of toxic effects when ivermectin is used at high oral doses or misused (including veterinary formulations), dominated by central‑nervous‑system depre...

Jan 7, 2026
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How soon after exposure do ivermectin toxicity symptoms appear compared with allergic reactions?

Ivermectin adverse effects follow multiple timelines: toxic neurologic or gastrointestinal effects from large or inappropriate doses can appear within hours, while parasite-related reactions and many ...

Feb 1, 2026

What are the clinical signs and timeline of ivermectin overdose in adults and children?

in humans most commonly produces gastrointestinal upset, circulatory instability and a range of neurological symptoms that can progress from lethargy and confusion to seizures, coma and rarely death; ...

Jan 16, 2026

What are the differences in toxicity between veterinary and human formulations of ivermectin?

The clinical literature and poison‑center reporting show a consistent pattern: veterinary ivermectin exposures more often involve large, untested doses and formulations (pastes, solutions) that produc...

Jan 29, 2026

What harms and adverse‑event reports have been linked to human use of veterinary ivermectin products?

Use of veterinary ivermectin formulations in humans has been repeatedly linked to overdoses and a spectrum of adverse events—most commonly gastrointestinal symptoms and neurologic problems—and has pro...

Jan 27, 2026

What are the reported toxicities and pharmacokinetic barriers to achieving anticancer concentrations of ivermectin in humans?

shows repeated anticancer activity in cell culture and some animal models, but translating those effects to humans faces clear and : the concentrations that kill tumor cells in vitro are often in the ...

Jan 16, 2026

How does ivermectin toxicity from veterinary formulations differ clinically from toxicity at high human therapeutic doses?

Reports from poison centers and clinical series show two distinct clinical pictures: acute neurotoxicity after ingestion of veterinary ivermectin products taken in large doses or over short periods, v...

Feb 6, 2026

What safety incidents or poison-control data exist about people using veterinary ivermectin formulations?

Reports from U.S. poison-control centers and clinical toxicology series document a clear rise in human exposures to during the , with dozens of medically significant cases and multiple hospitalization...

Feb 5, 2026

What are the recognized symptoms of ivermectin overdose in adults and children?

produces a spectrum of mainly neurological and gastrointestinal symptoms, ranging from dizziness, nausea and vomiting to confusion, ataxia, seizures and, rarely, coma or death . Children and adults ca...

Feb 4, 2026

What documented harms have occurred when patients used ivermectin in place of standard oncology treatments?

Patients who substitute ivermectin for evidence-based have suffered documented harms including (notably neurological effects at high doses and common gastrointestinal/skin reactions), dangerous drug–d...

Feb 1, 2026

Which laboratory tests and imaging studies help differentiate ivermectin toxicity from other neurotoxic exposures?

is diagnosed primarily by history and clinical features; there is no routinely useful clinical assay for ivermectin concentration, so laboratory and imaging testing mainly serve to rule out metabolic,...

Jan 25, 2026

What mechanisms explain how ivermectin could alter vitamin K‑dependent clotting factors in humans?

A small body of animal experiments, field trials, and case reports suggest can be associated with prolonged prothrombin time and reduced levels of –dependent clotting factors (II, VII, IX, X), but con...

Jan 25, 2026

What clinical evidence links specific veterinary solvents or preservatives to human toxicity after off‑label ivermectin ingestion?

Clinical reports and poison‑center data link severe human adverse events after off‑label ingestion of -formulations">veterinary ivermectin primarily to excessive ivermectin dosing and non‑oral or inap...

Jan 22, 2026

Are there reported case studies of adverse events when ivermectin is coadministered with chemotherapy supportive drugs?

No published case studies in the supplied reporting document a clear, directly attributed adverse event from coadministration of ivermectin specifically with chemotherapy supportive drugs; small clini...

Jan 20, 2026

What safety concerns and dose-limiting toxicities are associated with higher ivermectin doses?

High or “off‑label” ivermectin dosing raises two linked safety questions: are higher exposures intrinsically toxic, and do specific contexts (co‑infections, genetics, formulations, drug interactions) ...

Jan 18, 2026

Are there patient risk factors that make ivermectin toxicity more likely than a typical allergic response?

Yes—there are identifiable patient and situational risk factors that raise the likelihood of ivermectin toxicity (pharmacologic overdose or CNS/organ toxicity) beyond an immediate allergic reaction; p...

Jan 17, 2026

What official FDA statements and case reports exist about human poisonings from veterinary ivermectin?

The U.S. Food and Drug Administration (FDA) repeatedly warned that ivermectin is not authorized or approved to prevent or treat COVID‑19 in humans and alerted the public that people taking veterinary ...

Jan 17, 2026

What clinical features and outcomes distinguish toxicity from veterinary-formulated ivermectin versus human-dose ivermectin in published case series?

Published case series and poison‑center reviews show a clear pattern: toxicity linked to veterinary ivermectin is driven by higher ingested doses and unusual routes/formulations and presents with more...

Jan 17, 2026

What are the common side effects of ivermectin overdose?

Ivermectin overdose commonly produces gastrointestinal symptoms (nausea, vomiting, diarrhea), dizziness and other central nervous system effects (drowsiness, headache, tremor), and in more severe case...