Jan 19, 2026
Pycnogenol for ed
Pycnogenol, a French maritime pine bark extract, has been repeatedly studied for erectile dysfunction (ED) but almost always in combination with L‑arginine; combined therapy shows promising improvemen...
L-arginine and Erectile Dysfunction
The use of L-arginine, often in combination with Pycnogenol, for the treatment of erectile dysfunction, with studies suggesting a synergistic effect on sexual function.
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8 resultsJan 9, 2026
What does current clinical research say about l-arginine vs l-citrulline for erectile dysfunction effectiveness?
Clinical research shows both L-arginine and L-citrulline can modestly improve erectile function in some men, particularly those with mild to moderate or vasculogenic ED, but evidence is stronger and m...
Jan 9, 2026
What are safer, clinically proven alternatives for treating erectile dysfunction or penile size concerns?
Clinically proven, safer first-line treatments for erectile dysfunction (ED) center on lifestyle optimization and phosphodiesterase type 5 (PDE5) inhibitors such as sildenafil and tadalafil, with well...
Jan 8, 2026
What are the known drug interactions and contraindications for L‑arginine at doses used in ED trials (1.5–6 g/day)?
L‑arginine at doses used in erectile dysfunction (1.5–6 g/day) acts as a nitric oxide precursor and can meaningfully lower blood pressure and interact with drugs that affect vascular tone, hemostasis,...
Jan 8, 2026
How do common L‑arginine dosages in commercial supplements compare to doses used in clinical trials for ED?
Commercial L‑arginine supplements and clinical research overlap but are not identical: randomized trials for vasculogenic erectile dysfunction most commonly test moderate-to-high doses around 1.5–6 g/...
Jan 8, 2026
What clinical trials exist for L‑arginine or CBD in treating erectile dysfunction?
Clinical trial evidence supports some benefit of L‑arginine for mild-to-moderate erectile dysfunction (ED), both as a single high‑dose agent and in combination products—yet results are mixed across st...
Jan 8, 2026
What does high-quality clinical trial evidence say about l-arginine for erectile dysfunction?
High-quality randomized, double‑blind, placebo‑controlled trials provide mixed but cautiously optimistic evidence that oral L‑arginine can improve erectile function in some men, particularly those wit...
Jan 6, 2026
What does clinical research show about L‑arginine and zinc for erectile dysfunction?
Clinical trials and meta-analyses show that oral L‑arginine—an amino acid precursor to nitric oxide—has produced modest but statistically significant improvements in erectile function in men with mild...