factually
Index/Topics/L-arginine and L-citrulline supplements

L-arginine and L-citrulline supplements

The use of L-arginine and L-citrulline supplements for blood flow, exercise, and sexual performance, and their potential side effects and interactions.

Fact-Checks

2 results
Jan 25, 2026
Most Viewed

What are the common side effects and long-term safety data for using l-arginine or l-citrulline supplements?

are amino‑acid supplements commonly used to boost for blood‑flow, exercise and sexual performance, and they are generally tolerated in short clinical trials, but and blood‑pressure changes are the mos...

Jan 29, 2026

How do l‑citrulline and l‑arginine compare in increasing systemic arginine and nitric oxide in humans: pharmacokinetics and clinical implications?

consistently raises systemic L-arginine more effectively than equivalent doses of oral L-arginine because citrulline bypasses extensive presystemic arginase metabolism in the gut and liver, is readily...