Feb 6, 2026
How to actually lose weight?
reliably requires creating and sustaining a calorie deficit — eating fewer calories than the body uses — combined with behaviors that preserve muscle, reduce hunger, and improve adherence, not chasing...
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Structured and multi-component lifestyle programs, including diet, exercise, and behavioral support, that have shown modest but clinically relevant weight loss.
reliably requires creating and sustaining a calorie deficit — eating fewer calories than the body uses — combined with behaviors that preserve muscle, reduce hunger, and improve adherence, not chasing...
The strongest meta-analytic evidence for large, clinically meaningful weight loss comes from prescription obesity medications—specifically GLP‑1/GIP receptor agonists such as semaglutide and tirzepati...