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Infections caused by the Loa loa parasite, and the potential risks associated with ivermectin treatment.
Published human reports of ivermectin-associated neurotoxicity document either the drug’s detection in central nervous system tissue or clinical syndromes consistent with CNS penetration, but the revi...
Loss-of-function variants in the that abolish (P‑gp) efflux markedly increase , best documented as a 4‑bp deletion in herding‑breed dogs and as rare nonsense mutations in humans . Drugs that inhibit P...
Short-term ivermectin use at approved doses is generally associated with mild, self-limited effects — dizziness, headache, gastrointestinal upset, and transient skin reactions — while rare but serious...
Serious neurologic adverse events (encephalopathy, seizures, coma, persistent coma, ataxia) after ivermectin are uncommon but documented, and risk clusters around particular parasitic coinfections (no...
Documented human cases of ivermectin‑related neurotoxicity are rare but well described in the literature and fall into three broad patterns: mass‑treatment encephalopathies linked to parasitic coinfec...