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Mass drug administration campaigns for onchocerciasis and strongyloidiasis control
Mass drug administration (MDA) campaigns generally follow product labels and operational guidelines that instruct taking oral ivermectin on an empty stomach, but real-world practice balances that dire...
Clinical trials and protocols demonstrate that ivermectin has been given to humans at doses above 400 μg/kg—ranging from multiple trials testing 600 μg/kg and planned 1,200 μg/kg regimens to a formal ...
dosing for and is well established: onchocerciasis is typically treated with a single 150 micrograms per kilogram (mcg/kg) oral dose given at intervals (commonly annually) to suppress skin microfilari...
Clinical trials comparing (e.g., single 18 mg or 36 mg tablets) to standard weight‑based dosing (150–200 μg/kg) show broadly similar short‑term safety and tolerability in healthy adults, while fixed d...
Mass, scheduled treatments given to entire populations “every six months” are a feature of some parasitic-control campaigns but are not a universal practice for bacterial or parasitic infections world...
Mass drug administration (MDA) is the World Health Organization–recommended strategy to reduce morbidity from soil-transmitted helminths (STH) by treating high-risk groups (particularly school-aged ch...