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Mebendazole as a potential cancer treatment, particularly in combination with chemotherapy
A search of the provided reporting finds no definitive randomized controlled trials currently registered testing , or in cancer patients; what does exist are preclinical studies, case‑report compilati...
is the benzimidazole most advanced in human cancer testing and has been combined with chemotherapy in early‑phase clinical studies—most notably with in high‑grade glioma—showing safety signals and sug...
The public record for the three contains explicit hematologic toxicity definitions for the adult high‑grade glioma Phase I trial () but does not publish a complete, day‑by‑day CBC monitoring schedule ...
Phase‑1 clinical work repurposing —most notably a dose‑escalation trial in newly diagnosed high‑grade glioma—found “acceptable toxicity,” no severe adverse events attributed to mebendazole at doses up...
Randomized evidence testing mebendazole () combined with standard chemotherapy is extremely limited: a small, prospective randomized double‑blind placebo‑controlled trial in metastatic colorectal canc...