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The effect of various medications on orgasm and ejaculation in humans, including the role of serotonin, dopamine, and other pathways.
: for most people with male anatomy, ejaculating is accompanied by an orgasmic peak that is experienced as intense pleasure, a release of built-up tension, and brief autonomic changes such as increase...
are tightly linked in males but physiologically distinct: ejaculation is a peripheral, motor reflex composed of emission and expulsion under autonomic and somatic control, while orgasm is a transient ...
Premature ejaculation (PE) and delayed ejaculation (DE) sit at opposite ends of the ejaculatory spectrum, and age reshapes how often they appear, why they appear, and how clinicians classify them: PE ...
is mediated by a discrete spinal reflex circuit—the spinal ejaculation generator (SEG, including lumbar spinothalamic/LSt cells) that coordinates emission and expulsion through autonomic and somatic o...
Several medications can alter the usual coupling of orgasm and ejaculation—either by delaying or preventing semen emission while allowing the perceptual orgasm to occur, or by restoring orgasm when ej...