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Metabolic Rebound

The rebound effect on metabolism after discontinuing GLP-1 receptor agonists

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2 results
Jan 27, 2026

does synthetic glp1and gip from shots cause the body to stop producing natual GLP 1 and GIP?

Clinical and mechanistic reviews of and incretin-mimetic drugs show no documented evidence in the provided literature that injected synthetic GLP‑1 and dual GIP/GLP‑1 agonists make the body “stop prod...

Jan 18, 2026

What randomized evidence exists on cardiovascular outcomes after planned discontinuation of GLP‑1 therapy?

Randomized trial data directly assessing cardiovascular outcomes after a planned, protocolized discontinuation of GLP‑1 receptor agonists are scarce: most randomized controlled trials (RCTs) report ca...