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Index/Topics/Methylene Blue Efficacy and Safety

Methylene Blue Efficacy and Safety

The efficacy and safety of methylene blue and its derivatives, specifically hydromethylthionine, in human studies for various doses and formulations.

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Jan 27, 2026
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What dose ranges and formulations (hydromethylthionine vs methylene blue) have different safety and absorption profiles in human studies?

Two chemically related agents — classical (methylthioninium chloride, MTC) and a stabilized reduced derivative called hydromethylthionine (HMT; marketed as hydromethylthionine mesylate, HMTM or TRx023...

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