Jan 17, 2026
Which chemotherapies are most likely to interact pharmacologically with P‑glycoprotein inhibitors like ivermectin?
Ivermectin is both a substrate and inhibitor of P‑glycoprotein (ABCB1/P‑gp), and preclinical work identifies chemotherapies that rely on P‑gp for cellular efflux—most notably taxanes and vinca alkaloi...