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Index/Topics/NERVES Trial

NERVES Trial

A clinical trial comparing the outcomes of microdiscectomy and transforaminal epidural steroid injection for herniated-disc sciatica.

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2 results
Jan 20, 2026

Which patient factors predict poor outcomes or higher complication risk after ESIs?

Epidural steroid injection (ESI) outcomes are influenced by a mix of psychosocial, clinical and anatomical factors: preexisting psychological distress or depression, longer symptom chronicity, and und...

Jan 20, 2026

What are the most common complications after epidural steroid injections and how often do they occur?

Epidural steroid injections (ESIs) most commonly cause transient, minor problems—worse short-term pain, injection-site soreness and temporary numbness—occurring in roughly 2–9% of injections in publis...

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