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Neuroprotective effects of polyphenols

The preclinical literature converges on a handful of honey-derived polyphenols as the compounds with the strongest evidence for neuroprotective effects in cell, invertebrate and rodent models.

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Jan 19, 2026

Which components of honey (pinocembrin, chrysin, gallic acid) have human pharmacokinetic or safety data relevant to brain effects?

Pinocembrin is the only honey-derived compound among the three with published human pharmacokinetic and safety data relevant to potential brain effects, showing linear plasma kinetics after intravenou...

Jan 12, 2026

Which specific polyphenols in different honey types show the strongest evidence for neuroprotective activity in preclinical models?

The preclinical literature converges on a handful of honey-derived polyphenols—quercetin, apigenin, luteolin, pinocembrin, chrysin, myricetin, kaempferol and several phenolic acids (gallic, chlorogeni...