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The link between long-term nicotine gum use and insulin resistance, based on a 1996 clinical comparison and animal experiments.
The oft‑quoted link between “long‑term” nicotine gum use and insulin resistance rests primarily on a 1996 clinical comparison that described users as long‑term but—within the reporting provided—did no...
Two commercially available nicotine gums deliver either 2 mg or 4 mg of nicotine per piece, and trials and guidelines describe usage patterns ranging from “as needed” every 1–2 hours to regimented hou...
The 1996 Circulation paper by Eliasson et al. compared 20 long‑term users of nicotine gum with 20 matched nonusers and reported that long‑term gum use was associated with hyperinsulinemia and insulin ...