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The relationship between chewing nicotine gum and the development of type 2 diabetes in humans.
The oft‑quoted link between “long‑term” nicotine gum use and insulin resistance rests primarily on a 1996 clinical comparison that described users as long‑term but—within the reporting provided—did no...
Stopping nicotine tends to improve insulin sensitivity in humans, but the effect is partial, can be obscured by weight gain after quitting, and may be blunted if nicotine is replaced chronically (as w...
Chewing nicotine gum has been associated in human studies with markers that precede type 2 diabetes—specifically hyperinsulinemia and insulin resistance—most notably in a long‑term study of middle‑age...