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Nicotine Gum Strength Guidance

Guidance for choosing nicotine gum strength based on time-to-first-cigarette and cigarettes per day

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Jan 18, 2026
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What clinical guidance exists for tailoring nicotine gum dose by dependence measures such as time‑to‑first‑cigarette or cigarettes per day?

Clinical guidance for choosing nicotine gum strength (2 mg vs 4 mg) uses two related measures of dependence—time‑to‑first‑cigarette (TTFC) and cigarettes per day (CPD)—and both approaches are widely e...