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Nitric Oxide Synthesis

The role of nitric oxide synthesis in erectile function.

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Jan 14, 2026
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How does beet juice interact with lcitrline

Beetroot juice (nitrate-rich) and L‑citrulline act on two distinct biochemical routes that converge on nitric oxide (NO) production, and when combined they often—but not always—produce additive or syn...

Jan 19, 2026

Do combinations of L‑arginine with L‑citrulline or pycnogenol produce stronger or safer erectile function outcomes than L‑arginine alone?

Combination supplements pairing L‑arginine with either L‑citrulline or the pine‑bark extract Pycnogenol have produced stronger erectile‑function signals in small clinical trials and meta‑analyses than...

Jan 9, 2026

What does current clinical research say about l-arginine vs l-citrulline for erectile dysfunction effectiveness?

Clinical research shows both L-arginine and L-citrulline can modestly improve erectile function in some men, particularly those with mild to moderate or vasculogenic ED, but evidence is stronger and m...

Jan 8, 2026

What are the known drug interactions and contraindications for L‑arginine at doses used in ED trials (1.5–6 g/day)?

L‑arginine at doses used in erectile dysfunction (1.5–6 g/day) acts as a nitric oxide precursor and can meaningfully lower blood pressure and interact with drugs that affect vascular tone, hemostasis,...

Jan 8, 2026

What does high-quality clinical trial evidence say about l-arginine for erectile dysfunction?

High-quality randomized, double‑blind, placebo‑controlled trials provide mixed but cautiously optimistic evidence that oral L‑arginine can improve erectile function in some men, particularly those wit...

Jan 6, 2026

What does clinical research show about L‑arginine and zinc for erectile dysfunction?

Clinical trials and meta-analyses show that oral L‑arginine—an amino acid precursor to nitric oxide—has produced modest but statistically significant improvements in erectile function in men with mild...