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Index/Topics/Onchocerciasis

Onchocerciasis

A disease caused by the parasitic worm Onchocerca volvulus

Fact-Checks

4 results
Jan 27, 2026

What are the clinical features and management of the Mazzotti reaction after antiparasitic treatment?

The is an acute inflammatory syndrome that can follow microfilaricidal antiparasitic therapy, classically after for but also reported after , and other agents; it typically appears within hours to sev...

Jan 6, 2026

What are the recognized global public‑health uses of ivermectin in mass‑drug‑administration campaigns and their impacts?

Ivermectin has been deployed for decades in coordinated mass‑drug‑administration (MDA) campaigns primarily to control and, in some settings, eliminate onchocerciasis (river blindness) and lymphatic fi...

Jan 5, 2026

Short-term side effects of ivermectin treatment

Short-term side effects after a standard dose of ivermectin are usually mild and transient—most commonly itch, rash, fever, headache and gastrointestinal upset within the first few days following trea...

Jan 5, 2026

Which patient risk factors (e.g., dose, co-medications, preexisting CKD) increase risk of renal adverse events with ivermectin?

Clinical and pharmacovigilance data indicate that ivermectin is rarely linked to clinically meaningful renal injury in humans, but specific risk factors appear to increase the likelihood of transient ...

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