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Oral PDE5 Inhibitors

Use of oral PDE5 inhibitors as first-line therapy for erectile dysfunction

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Jan 18, 2026
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How do vacuum erection devices compare to other ED treatments in long-term safety?

Vacuum erection devices (VEDs) are a noninvasive, well‑established treatment for erectile dysfunction (ED) with consistently reported low long‑term morbidity and high continuation/satisfaction rates i...

Jan 31, 2026

How effective are topical ED creams compared with prescription PDE‑5 inhibitors in clinical trials?

—most robustly studied in the form of alprostadil formulations—have demonstrated clinically meaningful benefit in randomized trials and real‑world use, particularly for men who cannot take ; however, ...