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OTC weight loss ingredients

The effectiveness of over-the-counter weight loss ingredients, including spirulina, psyllium, glucomannan, green tea/coffee extracts, chitosan, curcumin, and Nigella sativa.

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Jan 12, 2026
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Which OTC supplement ingredients have randomized controlled trial data for modest weight loss, and what are their effect sizes?

Randomized controlled trials support modest average weight loss for a handful of over‑the‑counter (OTC) ingredients: notable meta-analytic estimates include spirulina (≈−1.77 kg), psyllium (≈−3.70 kg)...

Jan 18, 2026

What peer‑reviewed clinical evidence supports individual Lipoless ingredients (green tea extract, caffeine) for weight loss?

Clinical evidence for the two main Lipoless ingredients—green tea extract (predominantly EGCG) and caffeine—shows modest, inconsistent effects on body weight: randomized trials and meta-analyses repor...