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PDE-5 Inhibitors in Supplements

The most frequent undeclared ingredients in sexual-enhancement supplements are prescription phosphodiesterase-5 inhibitors (PDE-5 inhibitors) such as sildenafil or analogues.

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Jan 18, 2026

What FDA actions and warnings have targeted sexual‑enhancement supplements in the last decade?

The FDA has spent the last decade repeatedly warning consumers about sexual‑enhancement supplements that contain undeclared pharmaceutical ingredients, issuing public notifications, warning letters an...

Jan 7, 2026

Which sexual‑enhancement supplements have received FDA warnings for adulteration or false claims?

The FDA has repeatedly warned that dozens—and by some counts hundreds—of products marketed as sexual‑enhancement “supplements” are adulterated with undeclared prescription drugs or make false claims; ...