factually
Index/Topics/PDE5 Inhibitors for Erectile Dysfunction

PDE5 Inhibitors for Erectile Dysfunction

The use of PDE5 inhibitors as the first-line medical treatment for erectile dysfunction, comparing their efficacy and safety to common home remedies and botanical products.

Fact-Checks

2 results
Jan 19, 2026

What trial designs best test whether prior PDE5 inhibitor response modifies benefit from new ED therapies?

To test whether prior response to PDE5 inhibitors modifies benefit from a new erectile dysfunction (ED) therapy, the most reliable approaches are prospective randomized designs that stratify or random...

Jan 9, 2026

How do PDE5 inhibitors compare in safety and effectiveness to common home remedies for ED?

PDE5 inhibitors are the evidence-backed, first-line medical treatment for erectile dysfunction (ED), producing substantially higher success rates than placebo and a predictable safety profile when use...