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Index/Topics/PFOA Regulation

PFOA Regulation

Perfluorooctanoic acid (PFOA), one of the most regulated PFAS, was reported to have an absorption into the “bloodstream” equivalent of 13.5% of the applied dose in the study’s experimental setup.

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Jan 11, 2026

How do dermal absorption percentages from 3D skin models compare with in vivo human dermal studies for PFOA and short‑chain PFAS?

In vitro 3D human skin equivalent models report substantially higher dermal uptake fractions for many PFAS—including a PFOA permeation of ~13.5% with ~38% retained in skin and much larger fractions fo...

Jan 11, 2026

Which PFAS species have documented dermal absorption in 3D human skin models and what are their reported transfer rates?

A 2024 in vitro study using 3D human skin equivalent models tested 17 PFAS and found dermal uptake for most compounds: 15 of the 17 showed at least 5% systemic absorption under the study conditions (e...