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A 2023 pharmacogenomic analysis mapped interactions between ivermectin, selected antioxidants, and genes implicated in conditions such as diabetes and ischemia-reperfusion injury.
A high‑fat meal can increase systemic exposure to oral ivermectin by improving solubilization and absorption of this lipophilic drug, but the magnitude of that effect is inconsistent across studies an...
Ivermectin is primarily metabolized by hepatic CYP3A4 and is eliminated mostly in feces, so coadministration with other liver‑metabolized drugs or hepatic impairment can alter exposure and risk of tox...