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Index/Topics/Pre-Exposure Prophylaxis (PrEP)

Pre-Exposure Prophylaxis (PrEP)

Medication to prevent HIV infection

Fact-Checks

4 results
Jan 19, 2026

How should partners communicate and consent about hygiene and health before anal sex?

Clear, compassionate conversations about hygiene, STI status, protection, and boundaries are the core of safe and consensual anal sex; these talks should include practical plans (condoms, lube, hand/t...

Jan 7, 2026

What are evidence-based guidelines for when someone should see a doctor after anal play?

Anal play commonly causes mild soreness, fullness, or brief bleeding that can be managed with conservative aftercare, but specific red flags—severe or worsening pain, heavy or persistent bleeding, fev...

Jan 5, 2026

How does consistent PrEP use change the per-act HIV transmission risk for receptive anal sex?

Consistent use of oral or injectable PrEP cuts the per-act risk of acquiring HIV from receptive anal sex from roughly 138 infections per 10,000 exposures (about 1.38% per act) to on the order of 1 per...

Jan 5, 2026

What is the per-act HIV transmission risk for receptive versus insertive anal sex?

Per-act estimates used by major public-health bodies place the risk of HIV transmission from a single act of condomless anal sex at roughly 1.38% (138 per 10,000) for the receptive partner and about 0...

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