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Index/Topics/Preclinical studies on ivermectin

Preclinical studies on ivermectin

Preclinical studies demonstrating ivermectin's anticancer effects, including cytotoxicity, anti-proliferative, and anti-angiogenic effects in various cancer models.

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Jan 13, 2026
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How do plasma and tumor concentrations of ivermectin compare after standard oral dosing versus the multi-day oncology schedules?

Standard single-dose antiparasitic regimens of oral ivermectin produce plasma levels in the low nanomolar range, whereas multi‑day oncology schedules being tested raise both total exposure and peak le...

Jan 18, 2026
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Which cancers showed the strongest preclinical response to ivermectin and by what mechanisms?

Preclinical work identifies strongest anticancer signals for ivermectin in breast cancer, hematologic malignancies (notably leukemia), hepatocellular carcinoma, and several drug-resistant solid tumor ...

Jan 7, 2026
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What known drug–drug interactions exist between ivermectin and common chemotherapy or targeted agents?

Preclinical literature shows repeated, drug‑level interactions between ivermectin and multiple chemotherapy or targeted agents—mostly beneficial pharmacodynamic synergies (enhanced tumor cell kill, re...

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