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Prostate cancer treatment guidelines

Guidelines and recommendations for treating prostate cancer, including the use of PSA thresholds and imaging protocols

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Jan 19, 2026

How do PSA level and PSA doubling time influence the sensitivity of mpMRI for detecting local recurrence after prostatectomy?

Multiparametric MRI (mpMRI) is a powerful tool for localizing recurrence after radical prostatectomy, but its sensitivity is strongly influenced by the absolute PSA at biochemical recurrence and by PS...

Jan 18, 2026

How do free/total PSA ratio and PSA velocity compare to PSA density in predicting clinically significant prostate cancer?

A consistent theme across the literature is that no single PSA derivative is a perfect gatekeeper for clinically significant prostate cancer: percent free PSA (free/total, f/t PSA) improves discrimina...