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The use and interpretation of PSA testing in the context of acute bacterial prostatitis.
Gleason score and PSA doubling time (PSADT) are strong, largely independent predictors of metastatic progression after radical prostatectomy, with higher Gleason grades and shorter PSADTs both linked ...
Yes — a rise in prostate‑specific antigen (PSA) after radical prostatectomy is commonly the earliest laboratory sign that prostate cancer may have recurred, but interpretation depends on timing, magni...
Modern "ultrasensitive" PSA assays push analytic detection down into the picogram-per-milliliter range—commonly reported as limits between roughly 0.001 and 0.003 ng/mL (1–3 pg/µL) and historically as...
reliably raises serum PSA, but the time for PSA to fall back to a patient’s baseline is variable in the literature — typically weeks rather than days; most authoritative reviews and guidelines advise ...
Large prospective analyses find a modest inverse association between higher ejaculation frequency and subsequent prostate cancer diagnosis, with signals that the protective association appears across ...
A consistent theme across the literature is that no single PSA derivative is a perfect gatekeeper for clinically significant prostate cancer: percent free PSA (free/total, f/t PSA) improves discrimina...
Studies linking sexual activity to prostate cancer risk have grappled with the fact that prostate-specific antigen (PSA) both drives case ascertainment and is itself altered by sexual behavior; invest...